Doris Duke Charitable Foundation
Fellows

2008-09

 LaMont Barlow
Medical School: P&S
Department: Urology
Projects: 1) A Phase I Trial of Intravesical Nanoparticle Albumin-Bound Paclitaxel in the Treatment of BCG Refractory Nonmuscle Invasive Transitional Cell Carcinoma
2) A Single Institution Experience with Induction And Maintenance Intravesical Docetaxel in the Management of Non-Muscle Invasive Bladder Cancer Refractory to BCG Therapy
3) Is Age at the Time of Surgery a Predictor of Biochemical Failure Following Radical Prostatectomy?
4) Has the Advent of Minimally Invasive Surgery Altered the Risk Profile of Patients Undergoing Prostatectomy?
5) The Robotic Era of Radical Prostatectomy: A Retrospective Analysis of Patient Characteristics in Contemporary Robotic and Open Prostatectomy
6) Body Mass Index as an Independent Predictor of Intraoperative Ischemia Time During Partial Nephrectomy
7) Predicting Renal Functional Outcomes after Surgery for Renal Cortical Tumors: A Multifactorial Retrospective Analysis
8) The Pathologic and Clinical Outcomes of Men with Microfocal Prostate Cancer Undergoing Radical Prostatectomy
9) Evidence of Medical Renal Disease in Surrounding Renal Parenchyma and its Effect on Onset of Chronic Renal Insufficiency after Renal Surgery
10) Single Institutional Experience with Nephron Sparing Surgery for Pathological Stage T3bN0M0 Renal Cell Carcinoma Confined to the Renal Vein
11) Long Term Clinical Outcomes of a Phase I Trial of Intravesical Docetaxel in the Management of Non-Muscle-Invasive Bladder Cancer Refractory to Standard Intravesical Therapy
12) Tumor Maximum Diameter Independently Predicts eGFR in Patients With Renal Cell Carcinoma
Mentor: James McKiernan, M.D.
 Priya Batra
Medical School: P&S
Department: Medicine/Infectious Diseases (Global Health-International Program)
Project: 1) Excisional Therapy Outcomes for Cervical Intraepithelial Neoplasia (CIN) in a South African Population with High Human Immunodeficiency Virus (HIV) Prevalence
2) Cervical Cancer Prevention and Human Immunodeficiency Virus (HIV) Care in Cape Town, South Africa: Linking Services for Women at Risk
3) Taking A Closer Look: Evaluating Colposcopy in a Population at High Risk for Cervical Cancer
Mentors: Lynette Denny, M.D. (Groote Schuur Hospital, University of Cape Town, South Africa)
Scott Hammer, M.D.
Louise Kuhn, M.D.
Magda Sobieszczyk, M.D.
 Laura Brenner
Medical School: P&S
Department: Pediatrics/Molecular Genetics
Project: Linkage to 3p14.1 in a Family with Waardenburg Syndrome
Mentor: Wendy Chung, M.D.
 Ryan Cassilly
Medical School: P&S
Department: Orthopedic Surgery
Project: 1) MRI Evaluation of Teres Minor Hypertrophy And Functional Status in Patients with Massive Rotator Cuff Tears
2) Development of Pretibial Cysts after ACL Reconstruction with Bioabsorbable Tibial Interference Screws
Mentor: William Levine, M.D.
 Isaac Chan
Medical School: P&S
Department: Neurological Surgery
Project: Characterizing the Expression of PDGFRα, p53, and PTEN in Glioblastoma Multiforme via Tissue Microarray Analysis
Mentors: Jeffrey Bruce, M.D.
 Aileen Chang
Medical School: P&S
Department: Medicine/Infectious Diseases (Global Health-International Program)
Project: The Development and Evaluation of a Low Cost GIS-Based Dengue Surveillance System for Developing Countries
Mentor: Evelyn Campos, M.D. (Ministerio de Salud [MINSA], Managua, Nicaragua)
Scott Hammer, M.D.
Magda Sobieszczyk, M.D.
 Anthony Ding
Medical School: P&S
Department: Orthopedic Surgery
Project: 1) Atypical Fractures Associated with Long-Term Bisphosphonate Use
2) The Effect of Intercarpal Ligament Injuries on Distal Radius Fracture Outcomes
Mentor: Melvin Rosenwasser, M.D.
 Erica Farrand
Medical School: P&S
Department: Medicine/Digestive and Liver Diseases
Projects: 1) Basiliximab Induction and Delayed Calcineurin Inhibitor Initiation in Liver Transplant Recipients with Renal Failure
2) The Impact of DonorNet on the Short Term Graft Survival, Donor Risk Index and Time to Liver Transplantation
Mentor: Robert Brown, M.D.
 Catherine Forster
Medical School: Jefferson Medical College
Department: Medicine/Nephrology
Projects: 1) NGAL Identifies Bactermia Secondary to Urinary Tract Infection
2) Urinary Neutrophil Gelatinase Associated Lipocalin Distinguishes Type of Kidney Failure and Predicts Mortality in Patients with Cirrhosis
3) Urinary Neutrophil Gelatinase Associated Lipocalin Identifies Tubular Disease in HIVAN
4) A Single Measurement of Urine NGAL in the Emergency Department for the Diagnosis of Acute Kidney Injury: A Multicenter Study
5) NGAL Correlates with Tubulointerstitial Damage on Renal Biopsy
6) NGAL Predicts AKI in a Hypotensive Patient Population
7) Urine NGAL is a Superior Diagnostic Marker of Urinary Obstruction than Serum Creatinine
Mentor: Jonathan Barasch, M.D., Ph.D.
 Jeanne Franzone
Medical School: P&S
Department: Orthopedic Surgery
Projects: 1) Development of a Measure of Cam Impingement Severity in the Context of Slipped Capital Femoral Epiphysis
2) The Impact of Parental Compliance, Psychosocial Factors, and Severity on Clubfoot Treatment Outcome
3) Predicting a Need for Post-Tenotomy Casting to Correct Mild Deformity Recurrence During the Ponseti Method of Clubfoot Treatment
4) The Effect of Chronicity of Patellar Instability and Other Factors on Patellofemoral Cartilage Status: An Arthroscopic Assessment of Chondral Injury
Mentor: Michael Vitale, M.D.
 Olivia Fu
Medical School: Duke University School of Medicine
Department: Medicine/Hematology and Oncology
Project: Persistent Treatment-Related Symptoms Associated with Ethnicity and Employment in Breast Cancer Survivors
Mentor: Dawn Hershman, M.D.
 Bartosz Grobelny
Medical School: Jefferson Medical College
Department: Neurological Surgery
Projects: 1) Renal Dysfunction as an Independent Predictor of Outcome after Aneurysmal Subarachnoid Hemorrhage: A Single-Center Cohort Study
2) Cystathionine Beta-Synthase Gene Polymorphism is Associated with Increased Risk for Cerebral Vasospasm after Subarachnoid Hemorrhage
3) Preoperative Antiepileptic Drug Administration and the Incidence of Postoperative Seizures Following Bur Hole-Treated Chronic Subdural Hematoma
Mentor: E. Sander Connolly, Jr., M.D.
 Jacob Kaufman
Medical School: P&S
Department: Radiology
Projects: Cohesion Maps of Structural and Functional Connectivity
Mentor: Joy Hirsch, Ph.D.
 David Kent
Medical School: P&S
Department: Otolaryngology
Project: Linkage and Association Modeling of Candidate Genes in Non-Syndromic Cleft Lip and Palate in the Honduran Population
Mentor: Joseph Haddad, M.D.
 Daniel Lee
Medical School: School of Medicine at Stony Brook University Medical Center
Department: Urology
Projects: 1) Evaluation of Patient Outcomes in Robotic-Assisted and Surgical Urologic Oncology
2) Evaluation of Prostate Cancer Recurrence Among African-American Men
3) Evaluation of Socioeconomic, Cultural, and Behavioral Factors that Affect Screening Practices Among Afro-Caribbean and African-American Men
Mentors: James McKiernan, M.D.
Benjamin Spencer, M.D.
Ketan Badani, M.D.
 Eun-Ju Lee (funded in part by the National Institutes of Health/NIDDK)
Medical School: P&S
Department: Pediatrics/Endocrinology
Projects: 1) Effect of Laparoscopic Adjustable Gastric Banding (LAGB) on Metabolic Syndrome & its Risk Factors in Morbidly Obese Adolescents
2) Waist Circumference (WC) and Trunk Fat (TF) Correlate with Insulin Resistance (IR) and Cardiovascular (CV) Risk in Prepubertal Girls with Premature Adrenarche (PA)
3) Waist Circumference (WC) to Height Ratio (WHtR) Correlates with Markers of Insulin Resistance (IR) in Prepubertal Girls with Premature Adrenarche (PA)
4) Visceral Adipose Tissue and Subcutaneous Adipose Tissue Correlate with IGF-1, Insulin Resistance and Cardiovascular Risk Factors in Prepubertal Girls with Premature Adrenarche
5) Retinol Binding Protein: A Possible New Marker for Insulin Resistance in Children with Premature Adrenarche?
Mentor: Sharon Oberfield, M.D.
 Leslie Lee
Medical School: P&S
Department: Radiology
Projects: 1) Temporal Trends in Stroke Care in the US, 1998-2006
2) A Review of Hypothermia Trials in the Setting of Acute Ischemic Stroke
3) Cerebrovascular Reactivity and Cerebral Autoregulation in Normal Subjects
4) A Trial of Intra-Arterial Infusion of Cold Saline
5) Effectiveness of Embolic Protection Devices in Carotid Stenting
6) Underlying Cancer Diagnoses, Treatment Patterns, and Mortality in Hospitalizations for Malignant Spinal Cord Compression in the United States, 1998-2006
Mentor: John Pile-Spellman M.D.
 Robert McGovern
Medical School: P&S
Department: Neurological Surgery
Project: Quantitative Motor Examination in Normal Pressure Hydrocephalus and Parkinson's Disease
Mentor: Guy McKhann, M.D.
 Jason Prasso
Medical School: P&S
Department: Medicine/Infectious Diseases (Global Health-International Program)
Project: Intensified Case Finding for Active Tuberculosis among Adults Enrolled in HIV Care and Treatment at an Urban Hospital in Mozambique
Mentor: Elaine Abrams, M.D.
Scott Hammer, M.D.
Magda Sobieszczyk, M.D.
 Marie Roguski
Medical School: P&S
Department: Neurological Surgery
Project: Pre-operative MRI Characteristics and Prognosis of Glioblastoma Multiforme
Mentors: Jeffrey Bruce, M.D.
Peter Canoll, M.D. (Pathology)
 Catherine Seager
Medical School: P&S
Department: Urology
Project: 1) Combinatorial Inactivation of p53 and Pten Promotes Invasive Bladder Cancer
2) Delayed Prostatectomy and Biochemical Failure: Is there an Advantage to Early Surgery?
Mentor: James McKiernan, M.D.
 Laura Vickers
Medical School: Mount Sinai School of Medicine
Department: Ophthalmology
Project: Derivation of Functional Retinal Pigmented Epithelium from Human Embryonic Stem Cells Cultured on Bruch's Membrane
Mentor: Lucian Del Priore, M.D.
 Zachary Wright
Medical School: P&S
Department: Neurological Surgery
Project: 1) Pathological Changes Following Implantation of Human Microelectrode Grid Arrays
2) Gene and Local and Systemic Protein Expression in Human Brain Arteriovenous Malformations in Response to Therapeutic Intervention
Mentor: Guy McKhann, M.D.


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